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SWHR Isis Fund Network on Sex Differences in Musculoskeletal Health
March 2007 – Present

Mission Statement: Advance translational research on musculoskeletal health in women and men.

Achievements

Publications

  • Bredbenner, T.L., Eliason, T.D., Potter, R.S., Mason, R.L., Havill, L.M., and Nicolella, D.P. 2010. Statistical shape modeling describes variation in tibia and femur surface geometry between Control and Incidence groups from the osteoarthritis initiative database. J Biomech. Jun 18; 43(9):1780-6. Epub 2010 Mar 15.

Pilot Projects

  • Title: Determination of Sex Differences, Heritability, and Sex-specific Genetic Effects on Knee Arthritis in a Non-human Primate Model
    • PIs: Daniel Nicolella, Richard Coutts, Lorena Havill (Southwest Foundation for Biomedical Research)

Further Funding Resulting from Pilot Project Data

  • Title: Genetic Contributions to Knee Osteoarthritis Risk
    • Award Recipient: Lorena M. Havill, Ph.D. (Isis Network External Co-Investigator)
    • Institution: Southwest Foundation for Biomedical Research, San Antonio, TX
    • Amount: $450,000 (Over 3 Years)
    • Year of Grant: 2010

Symposia Presented 

February 2009: Instructional Course Lecture at the Annual Meeting of the American Academy of Orthoepadic Surgeons

  • Title: Sex and Gender Differences in Knee Osteoarthritis: Impact on Clinical Practice 
  • Chair: Barbara Boyan, PhD
  • Speakers:
    • Mary O’Connor, MD: Sex and Gender Differences in Knee Osteoarthritis: Surgeon’s Perspective
    • Wendy Kohrt, PhD: Clinical Evidence for Relationships of Exercise, Obesity, and Gender with OA
    • Daniel Nicolella, PhD: The Relationship between Osteoporosis and Bone Quality and the Development of Knee Osteoarthritis

June 2009: 3rd Annual Meeting of the Organization for the Study of Sex Differences

  • Title: Sex and Gender Differences in Knee Osteoarthritis (OA) 
  • Chair: Barbara Boyan, PhD
  • Speakers:
    • Mary O’Connor, MD: Sex and Gender Differences in Knee Osteoarthritis: Clinical Symptoms and Surgical Outcomes
    • Wendy Kohrt, PhD: Clinical Evidence for Relationships of Exercise, Obesity, and Gender with OA
    • Daniel Nicolella, PhD: The Relationship between Osteoporosis and Osteoarthritis
    • Amy Lerner, PhD (University of Rochester): Interactions between Obesity and Sex Differences in Knee Biomechanics and Osteoarthritis

Members

Karen Berkley, PhD
Florida State University
Wendy Kohrt, PhD
University of Colorado
Barbara Boyan, PhD (Network Chair)
Emory University, Georgia Institute of Technology
Kent Kwoh, MD
University of Pittsburgh
Laurence Bradley, PhD
University of Alabama at Birmingham
Daniel Nicolella, PhD
Southwest Biomedical Research Institute
Richard Coutts, MD
University of California, San Diego
Mary O’Connor, MD
Mayo Clinic
Roger M. Enoka, PhD
University of Colorado
Laura Tosi, MD
George Washington University
David A. Hart, PhD
University of Calgary
 

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