SWHR Isis Fund Network on Sex Differences in Metabolism
August 2003 – March 2009

Mission Statement: Advance the understanding of sex-dependent differences in energy homeostasis and metabolic disorders.

Achievements

Publications

• Peer Reviewed Articles
• Clegg D.J., Fried S.K., Greenberg A.S., Xiao Q.X., and Grove, K.L. 2010. A Microarray Analysis of Sexual Dimorphism of Adipose Tissues in High Fat Diet-Induced Obese Mice. International Journal of Obesity. (accepted)
  Read the Article Online
• Pasarica M., Sereda O.R., Redman L. M., Albarado D.C., Hymel D.T.,Roan L.E., Rood J.C., Burk D.H., and Smith S.R. 2009. Reduced Adipose Tissue Oxygenation in Human Obesity Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response. Diabetes. Vol. 58: 718

Network Project

• The Adiposite: A web portal for researchers on obesity and adipose tissue.  For more information visit: www.adiposite.org

Pilot Projects

• Title: Sex Differences in Gene Expression in Murine Adipose Tissue
• PIs: Deborah Clegg, Randy Seeley, Kevin Grove
• Title: Sex Differences in Gene Expression in Human Adipose Tissue
• PIs: Jennifer Lovejoy, Jeff Chang, Susan Fried, Steven Smith

Symposia Presented

February 2008: Molecular Control of Adipogenesis and Obesity Keystone Symposia

• Title: Preliminary analysis of the mouse gene expression data (from pilot project)
• Speakers:
• Deborah Clegg
• Kevin Grove

March 2008: International Association for the Study of Obesity Stock Conference

• Title: Sex and Obesity: Gender Differences in Energy Homeostasis and Fat Metabolism.
• Speakers:
• Jennifer Lovejoy
• Susan Fried
• Steven Smith
• Nori Geary

Members