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THE CAUSE AND EFFECT OF MIGRAINES

Jennifer Wider, MD
SWHR, Contributing Writer
March 20, 2012

A migraine is the most common type of headache that propels patients to seek care from their doctors. Roughly 30 million Americans suffer from migraine headaches, with women affected almost three times more often than men, according to statistics from the National Headache Foundation in Chicago.

“Hormonal changes are a big contributor to the higher female incidence,” said Michael A. Moskowitz, MD, Professor of Neurology at Harvard Medical School at the Massachusetts General Hospital in Boston. “There are lines of evidence that support this from lab to clinical evidence and a decrease (although not abolished) incidence in post-menopausal females.”

Migraine headaches can vary from person to person, but they typically last from four hours up to 72 hours. Some people get them several times per month, while others experience them much less frequently. Many migraine sufferers report throbbing or pulsating pain on one side of the head, blurred vision, sensitivity to light and sound, nausea, and vomiting.  Roughly one in five migraine sufferers experience an aura, or visual or sensory disturbance, before the onset of the headache. Examples of an aura include: flashes of light, loss of vision, zig-zag lines, pins and needles in an arm or leg, and speech and language problems.

Several risk factors have been identified that increase a person’s chance of having migraines:

  • Family history: A significant majority of migraine sufferers have a family history of migraine attacks. For a person who has one or more first-degree relatives with migraine headaches, the likelihood rises substantially.
  • Age: Migraines typically affect people between the ages of 15-55. Most people have had their first attack by 40 years old.
  • Gender: Women are more likely to suffer from migraines than men.
  • Certain medical conditions: depression, anxiety, stroke, epilepsy, and high blood pressure are all associated with migraine headaches.
  • Hormonal changes: Women who suffer from migraines often find that the headaches have a pattern of recurrence just before or shortly after the onset of menstruation. The headaches may also change during pregnancy and/or menopause.

Migraines are vascular headaches but the exact cause is not fully understood. Some researchers believe that migraines occur when there are abnormal changes in the brain. When these changes occur, inflammation causes blood vessels to swell and press on nerves, which can result in pain.

Researchers have learned that certain triggers can set off migraine attacks. These triggers vary from person to person and can include: sleep disturbances, stress, weather changes, low blood sugar, dehydration, bright lights and loud noises, hormonal changes, foods that contain aspartame, foods that contain tyramine (fava beans, aged cheeses, soy products, etc.), caffeine, and alcohol.

Unfortunately, migraines have no known cure, but they can be managed effectively with the help of a health care provider. A variety of drugs can be used for pain relief and for prevention. Lifestyle changes are often recommended to identify and eliminate possible triggers that can set off an attack.

“Until recently there have been no treatments available to treat people who suffer from chronic migraines,” said Moskowitz. “Recently, a new medication has become available specifically to treat chronic migraine headaches, called onabotulinumtoxinA (Botox). Chronic migraine sufferers can derive significant benefit from this new form of therapy.”

Chronic migraine sufferers have also found relief in certain vitamins and other homeopathic remedies. But patients should check with their doctors for proper treatment protocols.

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For more information on the Society for Women’s Health Research please contact Rachel Griffith at 202-496-5001 or Rachel@swhr.org.

Jennifer Wider, M.D.Jennifer Wider, M.D., is a medical advisor for the Society for Women’s Health Research (SWHR), a national non-profit organization based in Washington D.C., widely recognized as the thought leader in research on sex differences and dedicated to improving women’s health through advocacy, education, and research.

Dr. Wider is a graduate of Princeton University and received her medical degree in 1999 from the Mount Sinai School of Medicine in New York City. She is frequently published in newspapers, magazines, and websites and has been a guest on the Today Show, CBS News, Fox News, Good Day New York, and a variety of cable channels. Dr. Wider hosts “Paging Dr. Wider,” a weekly segment on Sirius satellite radio for the Cosmopolitan magazine channel.

Dr. Wider is a past managing editor of the health channel at iVillage.com. She writes a monthly news service article for SWHR and is the author of the consumer health booklet “Just the Facts: What Women Need to Know about Sex Differences in Health” and the book “The Doctor’s Complete College Girls’ Health Guide: From Sex to Drugs to the Freshman Fifteen.”

 

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